October 1, 2023

Amyotrophic Lateral Sclerosis Symptoms – Stem Cell Therapy Benefits and Risks for ALS

In the medical sector, Amyotrophic Lateral Sclerosis (ALS) is also called Lou Gehrig’s disease. It is a progressive neurodegenerative disease that disturbs the nerve cells in your brain and spinal cord. It is distinguished by slow deterioration and death of the motor neurons.

The motor neurons are the nerve cells that control your voluntary muscle movements.

ALS symptoms
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ALS symptoms

The symptoms of ALS can vary from person to person, but as ALS progresses, individuals may experience –

1. Muscle weakness

ALS usually starts with weakness in one limb or one part of the body, such as the hand, arm, leg, or foot. The weakness may progress to other muscles in the body, making it difficult to move or perform tasks.

2. Muscle twitching

Also known as fasciculations, muscle twitching is a common early symptom of ALS. It may occur in any muscle but is most common in the arms, legs, and tongue.

3. Difficulty speaking or swallowing

As the disease progresses, people with ALS may have difficulty speaking or swallowing, which can make communication and eating more challenging.

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4. Muscle stiffness or spasticity

Some people with ALS may experience muscle stiffness or spasticity, which can make movement even more difficult.

5. Fatigue

People with ALS may experience fatigue or a feeling of weakness, even after resting.

ALS may experience weight loss
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6. Weight loss

As the disease progresses, people with ALS may experience weight loss or muscle wasting.

These symptoms can even be triggered due to other medical issues. If you are experiencing any of the above symptoms it’s important to see a doctor at Stemwell Regenerative Medicine Center for a proper diagnosis. You can get more details on stemwell.com

While there is currently no cure for ALS, there are treatments available that can help manage symptoms and improve the quality of life for individuals with the disease.

What is stem cell therapy?

Stem cell therapy for Amyotrophic Lateral Sclerosis (ALS) involves the use of stem cells to replace or repair damaged nerve cells in the brain and spinal cord. Stem cells are cells that have the ability to develop into various types of cells in the body, and can also help repair damaged tissue.

There are different types of stem cells that can be used for ALS treatment including

  • Embryonic stem cells – These cells are drawn from embryos.
  • Induced pluripotent stem cells (iPSCs) – These are created by reprogramming adult cells.
  • Mesenchymal stem cells – These are found in bone marrow, fat tissue, and other parts of the body.

The stem cells are typically injected into the patient’s spinal cord, where they can differentiate into nerve cells and help repair or replace the damaged cells. Stem cell therapy is still in the experimental stages for ALS and more research is needed to determine its safety and effectiveness.

While there is no cure for ALS, stem cell therapy may hold promise for slowing the progression of the disease and improving quality of life. However, like any medical treatment, there are potential benefits and risks to consider.

ALS treatment
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  1. Potential to slow or halt the progression of the disease.
  2. Improve symptoms and thus the patient’s quality of life.
  3. Fewer side effects than other treatments.


  1. Potential for rejection, which can trigger complications.
  2. Potential for tumor formation [if the stem cells used are not properly screened and tested]
  3. Uncertainty surrounding long-term safety and efficacy [there is limited data available on its long-term safety and efficacy].
  4. High cost and is possibly not covered under health insurance.

In summary, stem cell therapy for ALS may hold promise for slowing the progression of the disease and improving quality of life, but there are potential risks and uncertainties surrounding the treatment. It is important for people with ALS to discuss the potential benefits and risks of stem cell therapy with their healthcare provider before deciding on the course of treatment.

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